A simple blood test
screening for colorectal cancer and advanced precancerous lesions
SEPTIN9 Gene Methylation Testing:
- Simple blood draw
- No special preparation needed
- No stool sample to collect
- No changes to your diet or medicines
Introducing
SPOT-MAS CRC
A blood test detecting cancer‑associated DNA changes (methylation of the SEPTIN9 gene) released into the bloodstream by colorectal tumors
Sensitivity*
Specificity*
(*) The sensitivity for the advanced precancerous lesion (APL) group is 54.29%. Wu et al. (2024). BMC Cancer.
Find out:
Colorectal Cancer (CRC) Burden
Colorectal cancer (CRC) is common—but highly preventable and treatable when found early.
Colorectal Cancer At Different Stages2
- Sung H, CA Cancer J Clin. 2021. 2. American Cancer Society. Survival Rates for Colorectal Cancer. 2026.
What is SPOT-MAS CRC test?
A blood test that looks for tiny, cancer‑associated DNA changes (methylation of the SEPTIN9 gene) that can be released into your bloodstream by colorectal tumors
PCR Mixture
Detection
(*) The sensitivity for the advanced precancerous lesion (APL) group is 54.29%.
Disclaimer: SPOT‑MAS CRC is a screening blood test for average‑risk adults and does not diagnose colorectal cancer. A positive result requires follow‑up colonoscopy; a negative result does not rule out cancer or replace routine screening recommended by your clinician.
| SPOT-MAS portfolio | Scope | Technology |
|---|---|---|
| SPOT-MAS 10 | Multi-omics features of 10 cancer types: Breast, Lung, Liver-Biliary tract, Colorectum, Stomach, Ovary, Pancreas, Esophagus, Endometrium, Head & Neck |
|
| SPOT-MAS Lung | Multiple lung-specific DNA features | |
| SPOT-MAS CRC Pro | Multiple colorectum-specific DNA features | |
| SPOT-MAS CRC | Septin9 gene methylation status |
|
Who should consider SPOT-MAS CRC?
- Adults 45–75 at average risk: People without symptoms and without a significant family history of colorectal cancer who need routine screening
- People who decline or cannot undergo colonoscopy: Individuals who are unwilling or unable to have a colonoscopy but still want to be screened.
- Individuals between colonoscopy check‑ins: Individuals who want an additional, convenient screen between recommended colonoscopy intervals (as advised by a clinician).
Gene Solutions JSC
186 - 188 Nguyen Duy Duong, Ward 2, District 10, Ho Chi Minh City, Vietnam
Scan here to learn more about colorectal cancer risk and the SPOT-MAS test.