Gastric cancer is among the top five deadliest cancers globally and ranks as the third leading cause of cancer-related deaths in Asia (1). Early detection plays a critical role, with survival rates reaching 75% when diagnosed early, but only 7% at late stages (2). Unfortunately, no standard-of-care (SOC) screening method currently exists for early detection of this lethal disease.
In this video, we present a case report showcasing how the SPOT-MAS Multi-cancer Early Detection Test helped detect a ctDNA signal pointing to a stomach tumor (3). This signal prompted further diagnostic imaging, including a gastroscopy, leading to the identification of stage IIIA gastric antrum cancer in a 64-year-old male patient with no prior symptoms or family history of cancer. The detection allowed the patient to undergo a total gastrectomy with D2 lymph node dissection.
This case highlights the silent nature of stomach cancer and underscores the importance of advanced screening methods like the SPOT-MAS test. By detecting ctDNA signals from stomach tumors, the SPOT-MAS test can guide timely interventions.
Take control of your health by adopting healthier lifestyle habits and undergoing regular health screenings.
References:
(1) GLOBOCAN 2022
(2) The American Cancer Society’s (ACS) publication, Cancer Facts & Figures 2022 and Cancer Facts & Figures 2021; the ACS website; and the International Agency for Cancer Research website
(3) Luu Hong Dang Nguyen et al. 2024. A consultation and work-up diagnosis protocol for a multicancer early detection test: a case series study. Future Science OA, 10(1).